What term describes the irreversible cessation of all brain activity, often discussed in organ donation contexts?

• A. Coma
• B. Persistent vegetative state
• C. Brain death
• D. Neurological death

Answer: (C)

Irreversible cessation of all brain activity, including brainstem function, is described as brain death. This defines death in many jurisdictions and is the criterion used in organ donation contexts because the loss of all brain function is permanent, even if machines maintain circulation for a time. Coma is a state of unresponsiveness with some brain activity and potential for recovery, so it is not dead. A persistent vegetative state involves wakefulness without conscious awareness, with some brain activity remaining, not complete cessation. Neurological death is not as precise a term; brain death is the accepted clinical and legal standard.